Code:
awk -F, -vOFS=, '{SUM = 0; C = NF - 1; for (i=2; i<=NF; i++) SUM += $i; print $0, SUM, C - SUM, SUM / C, (C - SUM) / C}' file
U_TOP_LOGIC/U_HPB2/U_HBRIDGE2/i_core/i_paddr_reg_2_/Q,1,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,0,0,33,34,0.492537,0.507463
U_TOP_LOGIC/U_HPB2/U_HBRIDGE2/i_core/i_paddr_reg_4_/Q,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,0,0,33,34,0.492537,0.507463
U_TOP_LOGIC/U_HPB2/U_HBRIDGE2/i_core/i_paddr_reg_5_/Q,0,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,32,35,0.477612,0.522388
U_TOP_LOGIC/U_HPB2/U_HBRIDGE2/i_core/i_paddr_reg_3_/Q,1,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,1,1,0,0,0,0,33,34,0.492537,0.507463