Lack of IP Connectivity


 
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Old 03-05-2012
Lack of IP Connectivity

Hi

Can any one please help identify the issue in scenario 2:

Connectivity Diagram:
1) Distribution Switch----Int_Switch----LabSwitch(Fa1/0)----Terminal Ser
2) Distribution Swtich----Int_Swtich----LabSwitch(Fa2/0)----3640 Router

---all links are access links

Distribution Switch (int vlan 10 = 10.1.96.251/26)
Int_Switch (int vlan 10 = 10.1.96.196/26)
LabSwitch (int vlan 10 = 10.1.96.234/26)
Termial Ser (Int Eth0 = 10.1.96.254/26)
3640 Router (int Fa1/0 = 10.1.96.245/26)

Scenario1: I could able to successfully ping/telent Termianal server from my pc.

Scenario2: Can able to ping Distribution switch ip from 3640 router and vice versa. But cannot able to ping/telnet from my pc. I have also confiured a default router on router as 0.0.0.0 0.0.0.0 10.1.96.251 but still cannot able to ping. i have a default-gate 10.1.96.251 configured.

Can any one please help in scenario2, if I am missing some thing.

Thanks in advance.
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DISULFINDER(1)							   User Commands						    DISULFINDER(1)

NAME
disulfinder - cysteines disulfide bonding state and connectivity predictor SYNOPSIS
disulfinder [OPTIONS] DESCRIPTION
'disulfinder' is for predicting the disulfide bonding state of cysteines and their disulfide connectivity starting from sequence alone. Disulfide bridges play a major role in the stabilization of the folding process for several proteins. Prediction of disulfide bridges from sequence alone is therefore useful for the study of structural and functional properties of specific proteins. In addition, knowledge about the disulfide bonding state of cysteines may help the experimental structure determination process and may be useful in other genomic annotation tasks. 'disulfinder' predicts disulfide patterns in two computational stages: (1) the disulfide bonding state of each cysteine is predicted by a BRNN-SVM binary classifier; (2) cysteines that are known to participate in the formation of bridges are paired by a Recursive Neural Network to obtain a connectivity pattern. REFERENCES
A. Ceroni, A. Passerini, A. Vullo and P. Frasconi. DISULFIND: a Disulfide Bonding State and Cysteine Connectivity Prediction Server, Nucleic Acids Research, 34(Web Server issue):W177-W181, 2006. For the disulphide connectivity predictor see: A. Vullo and P. Frasconi. Disulfide Connectivity Prediction using Recursive Neural Networks and Evolutionary Information, Bioinformatics, 20, 653-659, 2004. For the cystein bonding state predictor see: P. Frasconi, A. Passerini, and A. Vullo. A Two-Stage SVM Architecture for Predicting the Disulfide Bonding State of Cysteines, Proc. IEEE Workshop on Neural Networks for Signal Processing, pp.25-34, 2002. A.Ceroni, P.Frasconi, A.Passerini and A.Vullo. Predicting the Disulfide Bonding State of Cysteines with Combinations of Kernel Machines, Journal of VLSI Signal Processing, 35, 287-295, 2003. OPTIONS
-a, --alternatives=NUMBER alternative connectivity patterns (default=3) -o, --output=DIR output dir where predictions will be saved (default=$PWD) -p, --psi2=FILE|DIR input in psi2 format (PSI-BLAST Matrix in ASCII), either a single file or a directory(?). Generate this with "blastpgp -j <N> -Q FILE" where N >= 2. -r, --rootdir=DIR work directory (default=~/disulfinder) -k, --pkgdatadir=DIR package data directory containing Models (default=/usr/share/disulfinder) -F, --format={html|ascii} output format type (default=ascii) -d --blastdb=DIR blastpgp -d option (default=/data/sp+trembl) -c, --cleanpred cleanup intermediate prediction files (default=false) -P, --usepssm use pssm instead of counts for profiles (default=false) -C, --knownbondingstate assume bonding state is known (one file for each chain in directory <rootdir>/Predictions/Bondstate/Viterbi) (default=false) -v, --version disulfinder version -?, --help help screen EXAMPLES
"disulfinder -a 1 -p /usr/share/doc/disulfinder/examples/res_id_41483.blastPsiMatTmb -o ./disulfinder_results_dir" FILES
/usr/share/disulfinder default package data directory ~/disulfinder default work directory RESTRICTIONS
The work directory is not cleaned up automatically. AUTHOR
Ceroni A, Passerini A, Vullo A, Frasconi P. Packaging by Laszlo Kajan <lkajan@rostlab.org> COPYRIGHT AND LICENSE
GPL SEE ALSO
See official web site for help: <http://disulfind.dsi.unifi.it/> DISULFIND: a disulfide bonding state and cysteine connectivity prediction server: <http://www.ncbi.nlm.nih.gov/pubmed/?term=16844986[uid]> 1.2.11 2012-04-07 DISULFINDER(1)

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