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Top Forums UNIX for Beginners Questions & Answers Calculate e raise to the power in awk | UNIX Post 303041158 by RudiC on Friday 15th of November 2019 04:46:20 PM
Old 11-15-2019
I get the same results as you do applying your script to your sample data. But, not knowing WHAT formula to apply under which conditions, I can't tell "what (you're) ... doing is right." And, I'm afraid, nobody without a profound background in genetics can.




Aside, your code might benefit (improved readability and understandability, ease of maintenance) from some structuring and, mayhap, simplification. Like e.g.
Code:
awk '
FNR == 1        {print $0,"weight"
                 next
                }

                {TMP =  exp (($2<=0.01) ? (1-$2)*25 : (0.5-$2)*0.5 )
                 print $0, TMP / (1 + TMP)
                }
'  file
SNP MAF weight
10:60523:T:G 0.013 0.560576
10:62010:C:T 0.01125 0.560792
10:69083:C:T 0.3581 0.51773
10:73537:G:A 0.005268 1


Last edited by RudiC; 11-15-2019 at 05:55 PM..
This User Gave Thanks to RudiC For This Post:
 

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WEIGHT(1)						      General Commands Manual							 WEIGHT(1)

NAME
weight - calculates sequence weights for an alignment SYNOPSIS
weight [-options] <alignment file> DESCRIPTION
This manual page documents briefly the weight command. weight is a program that calculates weights for a sequence alignment. OPTIONS
Available options: -b <f> Use BLOSUM weighting scheme at <f> fractional identity. -f <f> Filter out seqs w/ fractional ident > <x> [0-1]. -h Help; print version and usage info. -o <file> Save weight-annotated alignment in <outfile>. -p Use position based weight scheme (Henikoff & Henikoff). -s <n> Sample <n> sequences at random into a new alignment. -v Use Voronoi weight scheme (Sibbald & Argos). --informat <s> Specify alignment file format <s>. Allowed formats: SELEX, MSF, Clustal, a2m, PHYLIP. --quiet Suppress verbose banner. SEE ALSO
afetch(1), alistat(1), compalign(1), compstruct(1), revcomp(1), seqsplit(1), seqstat(1), sfetch(1), shuffle(1), sindex(1), sreformat(1), stranslate(1), AUTHOR
Sean Eddy HHMI/Department of Genetics Washington University School of Medicine 4444 Forest Park Blvd., Box 8510 St Louis, MO 63108 USA Phone: 1-314-362-7666 FAX : 1-314-362-2157 Email: eddy@genetics.wustl.edu This manual page was written by Nelson A. de Oliveira <naoliv@gmail.com>, for the Debian project (but may be used by others). Mon, 01 Aug 2005 15:28:08 -0300 WEIGHT(1)
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