If CLINSIG has a value in it of Benign, then for the particular line the Classification is Benign. So I guess if CLINSIG has a value in it then that is the Classification and none of the conditions are applied.

My actual dataset does have some fields with null values in it. but I filled in those with ., that is what I mean by there are no empty fields.

I am not sure what you mean by already, you are correct that only Classification is assigned a value.

The first condition does unconditionally set Classification to VUS. That seems to be working.

Condition 2 sets the Classification to the value of CLINSIG unless CLINSIG has multiple values in it like in line 3 of file (if there are multiple values in it they are separated by a |. If this is the case then Classification is Conflicting.

Condition 3 is only run on the lines where Func.IDP.refGene = UTR then the value of Classification is Likely Benign,
if CLINSIG is set to VUS, if it is any other value it is not changed.

Condition 4 is if the PopFreqMax > .01 then the Classification is Likely Benign unless there is a value other
then VUS there. If there is that means CLINSIG had a value already.

Condition 5 is only run if Func.IDP.refGene = spicing AND GeneDetail.IDP.refGene has +/- symbol in it AND the number
after it is > 10 then the value of Classification is Likely Benign, unless there is a value other
then VUS there. If there is that means CLINSIG had a value already.

Thank you .