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Hi. sorry to come back to this a day later, but I've found that the awk doesn't capture all the lines that I wanted.

I abbreviated the ids I gave you but I adjusted for that in the script you gave...

For comparison, the awk does the same task in 0.4 seconds.
Many thanks!

Great, thank you!
The grep works, but I was afraid it would also run too slowly. I just did a sample that searched 10,000 lines for 1,000 ids and it worked in about 2 seconds. I'm rather happy with...

I have a very large file (10,000,000 lines), that contains a sample id and a property of that sample. I have another file that contains around 1,000,000 lines with sample ids that I want to remove...