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Hello janshamsani,

Let's say following is your Input_file(I have taken data from your Input_file only as there was no line having value more than .25 so add one more line to it as follows.).

1 ...

Try:
awk -F'\t' '$1=="HIGH" && $2=="PASS" && ( $3==1 || $3==3 )' file

or do you mean:
awk -F'\t' '$1=="HIGH" && $2=="PASS" && $3~/1.*3|3.*1/' file
which could also be written as:
awk -F'\t'...