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In addition you could leave out the sed and use:

cat << EOF | ...
<VirtualHost *:80>

ServerName dev.${sitename}

DocumentRoot /var/www/html/www.${sitename}/

...

Have you tried:
sitename=$1
prodserver=$2
sed "s/changeme/$sitename/g" << EOF | ssh $prodserver "cat > /data/$sitename.conf"
<VirtualHost *:80>

ServerName dev.changeme

...