I think the below will capture lines 2-6, but not line 1 (looks like 018328) is being captured by the regex. Is the syntax correct or is there a better way? Thank you .
perl
Code:
if ($FuncrefGene !~ /exonic/i && $GeneDetailrefGene=~/\D(\d+)/) { # capture the digits into $1
if ($1 > 11) { #
$1 ||= 0; # Give it a value of zero if no numeric value was found.
$classification = 'Likely Benign'; # Reclassify intronic variants (with distance only) based on distance to exon > 10 to Likely Benign
}
}
else {
if ($FuncrefGene !~ /exonic/i && $GeneDetailrefGene=~/(\D\d+)/) { # capture the digits after any non-digit into $1
if ($1 > 11) { #
$1 ||= 0; # Give it a value of zero if no numeric value was found.
$classification = 'Likely Benign'; # Reclassify intronic variants (with distance only) based on distance to exon > 10 to Likely Benign
}
}
else {
if ($FuncrefGene !~ /exonic/i) {
my ($transcript) = ($GeneDetailrefGene) =~ /(?:\.\d+[+*-])/; # Get a numeric value if exists using (.) and (+/-) and capture digits into $transcript.
$transcript ||= 0; # Give it a value of zero if no numeric value was found.
$classification = 'Likely Benign' if $transcript > 11; # Reclassify intronic variants (following c. nomenclature) to Likely Benign if distance greater than 10
}
}
Hi
i am new to scripting. i have a file file.dat with content as :
CONTENT_STORAGE PERCENTAGE FLAG:
/storage_01 64% 0
/storage_02 17% 1
I need to update the value of FLAG for a particular CONTENT_STORAGE value
I have written the following code
#!/bin/sh
threshold=20... (1 Reply)
I have a text file like this:
subject1:LecturerA:10
subject2:LecturerA:40
if I was given string in column 1 and 2 (which are subject 1 and LecturerA) , i need to update 3rd field of that line containing that given string , which is, number 10 need to be updated to 100 ,for example.
The... (6 Replies)
I am trying to add a condition to the below perl that will capture the GTtag and place a specific string in the last field of each line. The problem is that the GT value used is not right after the tag rather it is a few fields away. The values should always be 0/1 or 1/2 and are in bold in the... (12 Replies)
In the tab-delimeted input file below I am trying to use awk to update the value in $2 if TYPE=ins in bold, by adding the value of
HRUN= in italics. In the below since in line 1 TYPE=ins the 117282541 value in $2 has 6 added because that is the value of HRUN=.
Hopefully the awk is a start but I... (2 Replies)
In the perl below I am trying to set/update the value of $14 (last field) in file2, using the matching NM_ in $12
or $9 in file2 with the NM_ in $2 of file1.
The lengths of $9 and $12 can be variable but what is consistent is the start pattern will always be NM_ and the end pattern is always
;... (4 Replies)
In the perl there is a default rule that sets f to VUS, and then a seris of rules that will change f based on the result that is
obtained from the rule. The code below is a rule that is supposed to be applicable to lines 2-4 because this rule just looks at the digit in f. So in line 2 f is 27... (4 Replies)
I have been reading old posts and trying to come up with a solution for the below: Use a tab-delimited input file to assign
point to variables that are used to update a specific field, Rank. I really couldn't find too much in the way of assigning points
to variable, but made an attempt at an awk... (4 Replies)
I have an input file with
A=xyz
B=pqr
I would want the value in Second Field (xyz or pqr) updated with a value present in Shell Variable based on the value passed in the first field. (A or B )
while read line
do
NEW_VALUE = `some functionality done on $line`
If $line=First Field-... (1 Reply)
Hi,
So awk is driving me crazy on this one. I have searched everywhere and read man, docs and every related post Google can find and still no luck. The actual files I need to run this on are sensitive in nature, but it is the same thing as if I needed to calculate weighted grades for multiple... (15 Replies)
Discussion started by: cotilloe
15 Replies
LEARN ABOUT DEBIAN
bio::map::geneposition
Bio::Map::GenePosition(3pm) User Contributed Perl Documentation Bio::Map::GenePosition(3pm)NAME
Bio::Map::GenePosition - A typed position, suitable for modelling the various
regions of a gene.
SYNOPSIS
use Bio::Map::GenePosition;
use Bio::Map::GeneMap;
# say that the first transcript of a particular gene on a particular map
# (species) is 1000bp long
my $map = Bio::Map:GeneMap->get(-universal_name => 'BRCA2',
-species => 'human');
my $gene = $map->gene;
Bio::Map::GenePosition->new(-map => $map,
-element => $gene,
-start => 0,
-length => 1000,
-type => 'transcript');
# say that the coding region of the gene starts 30bp into the first
# transcript
Bio::Map::GenePosition->new(-map => $map,
-element => $gene,
-start => 30,
-length => 600,
-type => 'coding');
# A GenePosition isa PositionWithSequence, so can have sequence associated
# with it
my $exon = Bio::Map::GenePosition->new(-map => $map,
-element => $gene,
-start => 0,
-type => 'exon',
-seq => 'ATGGGGTGGG');
my $length = $exon->length; # $length is 10
DESCRIPTION
Define where various sub-regions (transcripts, exons, introns etc.) of a gene are. Do this so that you can then go onto to model other
mappable elements as having positions 20bp upstream of transcript 2, or 10bp into intron 3 etc., all without having to know the absolute
position of anything.
See Bio::Map::GeneRelative and t/Map/Map.t for more example usage.
FEEDBACK
Mailing Lists
User feedback is an integral part of the evolution of this and other Bioperl modules. Send your comments and suggestions preferably to the
Bioperl mailing list. Your participation is much appreciated.
bioperl-l@bioperl.org - General discussion
http://bioperl.org/wiki/Mailing_lists - About the mailing lists
Support
Please direct usage questions or support issues to the mailing list:
bioperl-l@bioperl.org
rather than to the module maintainer directly. Many experienced and reponsive experts will be able look at the problem and quickly address
it. Please include a thorough description of the problem with code and data examples if at all possible.
Reporting Bugs
Report bugs to the Bioperl bug tracking system to help us keep track of the bugs and their resolution. Bug reports can be submitted via the
web:
https://redmine.open-bio.org/projects/bioperl/
AUTHOR - Sendu Bala
Email bix@sendu.me.uk
APPENDIX
The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _
new
Title : new
Usage : my $obj = Bio::Map::GenePosition->new();
Function: Builds a new Bio::Map::GenePosition object
Returns : Bio::Map::GenePosition
Args : -map => Bio::Map::GeneMap object
-element => Bio::Map::Gene object
-relative => Bio::Map::GeneRelative object
-type => 'transcript|coding|exon|intron', REQUIRED
-seq => string, length of this string will set the length
of this position's range
* If this position has no range, or if a single value can describe
the range *
-value => scalar : something that describes the single
point position or range of this
Position, most likely an int
* Or if this position has a range, at least two of *
-start => int : value of the start co-ordinate
-end => int : value of the end co-ordinate
-length => int : length of the range
map
Title : map
Usage : my $map = $position->map();
$position->map($map);
Function: Get/set the map the position is in.
Returns : L<Bio::Map::MapI>
Args : none to get
new L<Bio::Map::MapI> to set
element
Title : element
Usage : my $element = $position->element();
$position->element($element);
Function: Get/set the element the position is for.
Returns : L<Bio::Map::MappableI>
Args : none to get
new L<Bio::Map::MappableI> to set
type
Title : type
Usage : my $type = $position->type();
$position->type($type);
Function: Get/set the type of this position.
Returns : string
Args : none to get, OR
string transcript|coding|exon|intron to set
relative
Title : relative
Usage : my $relative = $position->relative();
$position->relative($relative);
Function: Get/set the thing this Position's coordinates (numerical(), start(),
end()) are relative to, as described by a RelativeI object.
Returns : Bio::Map::GeneRelative. The default GeneRelative returned has a
meaning that depends on the type() of GenePosition this is:
'transcript' : "relative to the start of the gene on the
Position's map"
'coding|exon|intron' : "relative to the start of the default
transcript of the gene on the Position's map"
Args : none to get, OR
Bio::Map::GeneRelative to set
seq
Title : seq
Usage : my $string = $position->seq();
Function: Get/set the sequence as a string of letters. If no sequence is
manually set by you, the position's map will be asked for the
sequence, and if available, that will be returned.
Returns : scalar
Args : Optionally on set the new value (a string). An optional second
argument presets the alphabet (otherwise it will be guessed).
perl v5.14.2 2012-03-02 Bio::Map::GenePosition(3pm)
09-11-2017
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