Moderator's Comments:

This is probably a question where opinion and technical facts border on one another. I am willing to give some leeway here, as long as this is not used to overstretch boundaries.

This is a good choice, IMHO, as long as you use mainly one VM, like Sean_ said he plans to do. I used it some years ago and especially liked two features: the ability to route USB ports to the virtual machine (this way you can use USB-based keycards, "identity sticks" and the like in the guest system) and the ability to create an image from an existing installation. I imaged the normal Windows-installation and used the image to boot the VM after installing (Fedora-)-Linux. This way i avoided troubles with the user-helpdesk because they didn't recognize that they were looking at a virtual (instead of physical) machine.

I think KVM/Quemu or OpenVZ is better suited for managing many concurrent VMs but this seems not to be Sean_'s intended use.

bakunin