Hello: I have another question. Please consider the following two sample, tab-delimited files:

File_1:

Abf1 YKL112w
Abf1 YAL054c
Abf1 YGL234w
Ace2 YKL150w
Ace2 YNL328c
Cup9 YDR441c
Cup9 YDR442w
Cup9 YEL040w
...


File 2:

...
ABF1 YKL112W
ACE2 YLR131C
CUP9 YPL177C
...

File_2 is a “lookup table;” I want to replace $1 in File_1 with the matching $2 field in File_2, additionally adding a middle column containing the string “tf”, and a column of “ones” (“1” in the first column position), all tab-delimited.

Additionally, it would be ideal if the case could be ignored for the search / replace, but that the alphabetical output be all uppercase [a-z] converted to [A-Z].

FYI, these are yeast genes; in addition to numbers and letters, some of the genes will contain dashes (e.g., YBR162W-A), but none will contain commas, semicolons, spaces, etc.

Output File_3:

1 YKL112W tf YKL112W
1 YKL112W tf YAL054C
1 YKL112W tf YGL234W
1 YLR131C tf YKL150W
1 YLR131C tf YNL328C
1 YLR131C tf YLR439W
1 YPL177C tf YDR441C
1 YPL177C tf YDR442W
1 YPL177C tf YEL040W
...

This is related to (but different from) my earlier query,

https://www.unix.com/shell-programmin...#post302183287

Here, the first column is a “dummy” weight value, to maintain “field compatibility,” with my earlier file, as shown in this example:

1 a gi b
1 a pp a
1 a pp c
1 t gi u
1 t gi w
1 t gi x
1 t pp z
2 a pp d
2 a pp e
2 t gi v
2 t gi z
3 a pp b
3 t gi y
...

Ultimately, I will end up with a file like this, with $1 = weight, $2 = gene1, $3 = association, $4 = gene2:


1 YKL112W tf YKL112W
1 YKL112W tf YAL054C
1 YKL112W tf YGL234W
1 YLR131C tf YKL150W
1 YLR131C tf YNL328C
1 YLR131C tf YLR439W
1 YPL177C tf YDR441C
1 YPL177C tf YDR442W
1 YPL177C tf YEL040W
...
1 YBL012C gi YCL045C
1 YBL012C pp YBL012C
5 YBL012C pp YHR039C-A
1 YLR363W-A gi YNL143C
4 YLR363W-A gi YPR123C
1 YLR363W-A gi YLR467W
1 YLR363W-A pp YNR073C
2 YBL012C pp YGL232W
2 YBL012C pp YOR102W
2 YLR363W-A gi YFL066C
2 YLR363W-A gi YNR073C
3 YBL012C pp YCL045C
3 YLR363W-A gi YKL100C
...

Thank you - Once again, *very* much appreciated!

Sincerely, Greg S. :-)