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Old 08-03-2009
Question Homework :(

1. You have a very large file, named 'ColMe', tab-delimited, you are asked to process. You are told that each line in 'ColMe' has 7 columns, and that the values in the 5th column are integers. Using shell functions (and standard LINUX/UNIX filters), indicate how you would verify that these conditions were satisfied in 'ColMe'. 2. In the same file, you are told that each value in column 1 is unique. How would you verify that?
3. Write a shell function that counts the number of occurrences of the word “SpecStr” in the file 'ColMe'.
4. Please show how you would do this in PERL, or related language.
 
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VCF-ISEC(1)							   User Commands						       VCF-ISEC(1)

NAME
vcf-isec - create intersections, unions, complements on bgzipped and tabix indexed VCF or tab-delimited files SYNOPSIS
vcf-isec [OPTIONS] file1.vcf file2.vcf ... DESCRIPTION
About: Create intersections, unions, complements on bgzipped and tabix indexed VCF or tab-delimited files. Note that lines from all files can be intermixed together on the output, which can yield unexpected results. OPTIONS
-C, --chromosomes <list|file> Process the given chromosomes (comma-separated list or one chromosome per line in a file). -c, --complement Output positions present in the first file but missing from the other files. -d, --debug Debugging information -f, --force Continue even if the script complains about differing columns. -o, --one-file-only Print only entries from the left-most file. Without -o, all unique positions will be printed. -n, --nfiles [+-=]<int> Output positions present in this many (=), this many or more (+), or this many or fewer (-) files. -p, --prefix <path> If present, multiple files will be created with all possible isec combinations. (Suitable for Venn Diagram analysis.) -t, --tab <chr:pos:file> Tab-delimited file with indexes of chromosome and position columns. (1-based indexes) -w, --win <int> In repetitive sequences, the same indel can be called at different positions. Consider records this far apart as matching (be it a SNP or an indel). -h, -?, --help This help message. EXAMPLES
bgzip file.vcf; tabix -p vcf file.vcf.gz bgzip file.tab; tabix -s 1 -b 2 -e 2 file.tab.gz vcf-isec 0.1.5 July 2011 VCF-ISEC(1)