Have you isolated what programs were being accessed by those addresses? Depending on what exactly your script is doing, it may not be a practical idea. Large companies often have gateways which will make it seem as if one person (one IP) is accessing hundreds of instances of a page. So imagine say 200 people at Cisco viewing your site. While you see it as one address, the fact is, there are many people viewing the site.

What is the overall purpose of your script. Considering I can spoof addresses, if your firewall is misconfigured, your provider isn't doing BCP filtering, as an attack vector, I can make your server ignore everything via 0.0.0.0 spoofing.