We've just completed a project using RedHat Ent Linux and an HP MSA1500 SAN.

Running the controllers in active/active mode we're using RedHats Device Mapper Multipath software to create multiple paths to our SAN.

I suspect the CentOS will have similar capabilities and be able to use Redhat RPMs for DM/DMMP.

Oh and the DM/DMMP technology is built on LVM so in a way you're still using LVM, I hope this helps you out a little.